St. Mark's Hospital - May 11, 2017

Antibiotic resistance is a patient safety issue.

Antibiotic stewardship consists of a set of clinical behaviors that reduce the development of multi-resistant organisms, reduce the risk of clostridia difficile enteritis, and reduce the antibiotic cost of care, without compromising clinical outcomes of antibiotic therapy.

These behaviors include:

  • Using antibiotics only for substantiated clinical indications.
  • Using the narrowest spectrum antibiotic appropriate to the clinical indication.
  • Switching to a targeted-spectrum antibiotic when the results are known from culture, PCR, or other molecular microbiology testing.
  • Administering evidence-based surgical antibiotic prophylaxis, and not extending prophylaxis without a documented appropriate clinical indication.
  • Switching from IV to oral antibiotics as soon as clinically appropriate.
  • Using surveillance systems, like VigiLanz currently in use at St. Mark’s, for real-time detection of “drug/bug” mismatches.

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