St. Mark's Hospital - May 11, 2017

Early rapid detection of specific infections aids in minimizing unnecessary antibiotic use.

The BioFire FilmArray Respiratory panel is now available through St. Mark’s laboratory. This panel tests for the following target pathogens:

Viral Targets

  • Adenovirus
  • Coronaviruses:  HKU1, NL63, 229E, OC43
  • Human metapneumovirus
  • Human rhinovirus / Enterovirus
  • Influenza A, A/H1, A/H3, A/H1-2009, B
  • Parainfluenza Virus 1,2,3,4
  • Respiratory syncytial virus

Bacterial Targets

  • Bordetella pertussis
  • Chlamydophila pneumoniae
  • Mycoplasma pneumonia

While consensus on guidelines for the appropriate use of this type of testing has not yet been firmly established, some published evidence suggests that use of such testing is significantly associated with decrease healthcare resource utilization in hospitalized patients, including decreased use of antibiotics and chest radiographs, and increased use of isolation precautions. Others argue that since most respiratory pathogens are viruses and since antiviral treatment availability is limited to very few viral pathogens, consistent use of such a test is not warranted unless it is specifically used to rule out one or more of the bacterial pathogens, to confirm the need for and type of hospital isolation, or to support a decision to discontinue parenteral antibiotics when a respiratory pathogen is in question.

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